Survival by IPI Staging System
IMF
International
Prognostic Index (IPI)
Staging for Multiple Myeloma
STAGE 1
2M < 3.5
ALB > 3.5
STAGE 2
2M < 3.5
ALB < 3.5
or
2M 3.5 ­ 5.5
STAGE 3
2M > 5.5
Footnote: 2M = serum 2 microglobulin in mg/l
ALB = serum albumin in g/dl
Good and Poor Risk Groups
· Age is the only additional factor
Factors Predicting Very Low Risk*
that significantly impacts outcome.
(>5 year survival)
·Survival for > 5 years is associated
with age < 60 years.
·Survival for < 2 years is associated
with age > 60 years. Other correlations
in this category include:
platelet count< 130,000/mm3 and
LDH serum level above normal.
·Cytogenetics do influence outcome,
however, chromosome 13 deletion and
presence of complex chromosome
abnormalities do not add to the
impact of age, 2M and ALB.
800.452.CURE (2873)
818.487.7455
International Myeloma Foundation
*Low Risk = Stage 1 Patients < Age 60
12650 Riverside Drive, Suite 206
North Hollywood, CA 91607-3421
www.myeloma.org
www.myeloma.org
"Until There is a Cure... There is the IMF."

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