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The Myeloma Matrix
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A comprehensive guide to new drugs in development for myeloma.
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CARFILZOMIB (PR-171)
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Carfilzomib is a new intravenously-administered proteasome inhibitor showing promise for the treatment of multiple myeloma.
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REVLIMID®
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REVLIMID®, a potent immunomodulatory derivative (IMiD) of thalidomide, induces apoptosis in resistant MM cell lines and patient cells and, more importantly, decreases binding of MM cells to bone marrow stromal cells.
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THALOMID®
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Clinical trials using thalidomide. If you would like to know more about thalidomide treatment for myeloma, click on the "living with myeloma" tab at the top, and then on "Treatments."
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VELCADE®
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The latest on clinical trials using VELCADE®. If you would like to know more about VELCADE®, click on the 'information & treatments' tab at the top, and then on 'Treatments' in the index on the left hand side of the page."
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VORINOSTAT (MK0683)
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Vorinostat is an HDAC inhibitor, which has shown promise in the treatment of multiple myeloma.
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CAFE Study - Cancer Patient Fracture Evaluation
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Cancer treatments, including chemotherapy and steroids, are associated with enhanced bone loss and increased fracture risk. This bone loss may lead to collapsed vertebrae in the spine, also known as vertebral body compression fractures (VCFs). The primary purpose of this study is to document how patients with VCFs function in every day activities after being treated with balloon kyphoplasty compared to those treated with non-surgical therapy alone. This information may help doctors treating cancer patients with broken backbones determine which treatment to recommend.
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National Cancer Institute CancerTrials
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The National Cancer Institute has an excellent web site, CancerTrials, with basic information about clinical trials and an extensive database of active trials.
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National Cancer Institute Multiple Myeloma Trial Results
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Summaries of Newsworthy Clinical Trial Results
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National Cancer Institute
Clinical Trials Educational Materials
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CenterWatch Clinical Trials Information
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Lisitngs of open clinical trials. Also includes background information about the clinical trials process, FDA drug approvals, and oncology research center profiles.
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EmergingMed Clinical Trials Search
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Confidential, free, online matching and referral system comparing patient profile (diagnosis, condition, and tx history) to trial entry criteria and locations.
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TrialCheck® Database
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TrialCheck® provides an extensive listing of cooperative group, NCI, and pharmaceutical clinical trials for cancer.
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Cancer Trials Support Unit - Efficient and Effective Tools for Clinical Trials Management.
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The Cancer Trials Support Unit (CTSU) is an NCI funded program to facilitate participation (by both patients and physicians) in phase III NCI sponsored Cancer treatment trials.
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Coalition Of National Cancer Cooperative Groups
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Cancer clinical trials are one of the most important weapons in the continuing fight against cancer. The coalition's mission is to improve the quality of life and the survival of people with cancer
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Eastern Cooperative Oncology Group
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ECOG is one of the largest clinical cancer research organizations in the United States, and conducts clinical trials in all types of adult cancers.
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Southwest Oncology Group
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SWOG is one of the largest of the National Cancer Institute-supported cancer clinical trials cooperative groups in the United States
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Clinical Trials at the Mayo Clinic
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Clinical Trials at the Myeloma Inst. for Research and Therapy at Arkansas Cancer Research Ctr.
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Clinical Trials at the Cleveland Clinic
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Clinical Trials at Roswell Park Cancer Institute in Buffalo
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Clinical trials offer patients access to promising new treatments which have not yet been approved. They offer an opportunity to help make new treatments available to all patients by helping to advance science. Patients in clinical trials receive high-quality care and are carefully followed. The IMF is pleased to offer a number of ways to help you locate a clinical trial which may be appropriate. 
