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A Comprehensive Guide to Kos 2007
Review of the XIth International Myeloma Workshop

2.11.08

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A Comprehensive Guide to Kos 2007
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The IMF is pleased to present the most comprehensive coverage of the XIth International Myeloma Workshop.

Day 1 Genetics Day 2 Novel treatment approaches
  Microenvironment   Frontline treatment of Myeloma
  Bone Disease   Debate I (Importance of CR)
      Oral presentations I
      Oral presentations II


Day 3 New treatment development Day 4 Oral presentations III
  Stem cell transplant   Debate II - Role of Transplant
  Other plasma cell dyscrasias   Current and Future Perspectives

 

:
06.26.07     KOS 2007: Molecular Principles Underlying Myeloma
  P. Leif Bergsagel, MD
Mayo Clinic
Scottsdale, AZ, USA
06.26.07     KOS 2007: Molecular Lesions in Multiple Myeloma
  Michael Kuehl, MD
National Cancer Institute
Bethesda, MD, USA
06.26.07     KOS 2007: Towards a Molecular-Based Risk Stratification of Multiple Myeloma
  J.D. Shaughnessy Jr., MD
Donna D. and Donald M. Lambert Laboratory for Myeloma Genetics
Myeloma Institute for Research and Therapy
University of Arkansas for Medical Sciences
Little Rock, Arkansas, USA
06.26.07     KOS 2007: Clinical and Pathological Implications of Myeloma Subtypes
  Rafael Fonseca, MD
Mayo Clinic
Scottsdale, AZ, USA
06.26.07     KOS 2007: Prognostic implications of FISH karyotyping in Myeloma
  Herve Avet-Loiseau, MD
Laboratory of Hematology
University Hospital
Nantes, France
06.26.07     KOS 2007: Single Nucleotide Polymorphism Models in Myeloma - From the Bank On A Cure SNP Chip
  Brian Van Ness, PhD
Bank On A Cure®
International Myeloma Foundation
:
06.26.07     KOS 2007: Animal Models of Multiple Myeloma: An Overview
  Karin Vanderkerken, MD
Vrije Universiteit Brussel (VUB)
Department Hematology and Immunology
Brussels, Belgium
06.26.07     KOS 2007: The Scid-hu model for Multiple Myeloma
  Joshua Epstein, MD
Myeloma Institute for Research and Therapy
University of Arkansas for Medical Sciences
Little Rock, Arkansas, USA
06.26.07     KOS 2007: Chromosomal and epigenetic abnormalities in MGUS and MM Post-MGUS
  Johannes Drach, MD
Medical University of Vienna
Department of Medicine I
Clinical Division of Oncology
Vienna, Austria
06.26.07     KOS 2007: Microarray Analysis to Predict Response to Thalidomide and the IMIDs
  Shaji Kumar, MD
Mayo Clinic
Hepatology Department
Rochester, MN, USA
06.26.07     KOS 2007: Mosaicism of Vessels in Patients with Myeloma and Therapeutic Approaches
Angelo Vacca, MD
Department of Internal Medicine and Clinical Oncology
University of Bari Medical School
Bari, Italy
06.26.07     KOS 2007: The Role of T-Cells in Multiple Myeloma
  Douglas Joshua, MD
University of Sydney
Royal Prince Alfred and Concord Hospital
Camperdown, Australia
06.26.07     KOS 2007: Genetic Model of Multiple Myeloma
Ruben Carrasco, MD
Dana Farber Cancer Institute
Medical Oncology Dept.
Boston, MA, USA
(Presentation given by Giovanni Tonon)
06.26.07     KOS 2007: From Oncogenome Mining to Functional Validation of Multiple Myeloma Cancer Genes
  Giovanni Tonon, MD
Dana Farber Cancer Institute
Medical Oncology Dept.
Boston, MA, USA
:
06.26.07     KOS 2007: Induction of Multi-Lineage Markers and Their Down-Regulation by IL-6 in Human Myeloma Cells
  Michio Kawano, MD
Laboratory of Cellular Signal Analysis
Graduate School of Medicine
Yamaguchi University
Ube, Japan
06.26.07     KOS 2007: Pathophysiology of Myeloma Bone Disease
  Peter Croucher, MD
Section of Musculoskeletal Science
University of Sheffield Medical School
Sheffield, UK
06.26.07     KOS 2007: The Role of Biochemical Markers of Bone Metabolism in Multiple Myeloma. Adverse Events of Bisphosphonates Administration
  Evangelos Terpos, MD
Department of Hematology & Medical Research
251 General Airforce Hospital
Athens, Greece
06.26.07     KOS 2007: The Role of Bisphosphonates in the Management of Myeloma
  James Berenson, MD
Institute for Myeloma and Bone Cancer Research
Los Angeles, CA, USA
06.26.07     KOS 2007: New Agents Targeting Myeloma Bone Disease
  G. David Roodman
University of Pittsburgh
Medicine/Hematology-Oncology
Pittsburgh, PA, USA
06.26.07     KOS 2007: A transgenic mouse model that faithfully reproduces the pathogenesis, biology and clinical features of multiple myeloma
  Marta Chesi, MD
Comprehensive Cancer Center
Mayo Clinic Arizona
Scottsdale, AZ, USA
:
06.27.07     KOS 2007: The Treatment of Relapsed and Refractory Myeloma: Focus on Bortezomib and Bortezomib-based Combinations
  Paul Richardson, MD
Medical Oncology
Dana Farber Cancer Institute
Harvard Medical School
Boston, MA, USA
06.27.07     KOS 2007: Lenalidomide for the Treatment of Relapsed or Refractory Myeloma
  Donna Weber, MD
The University of Texas MD Anderson Cancer Center
Houston, TX, USA
06.27.07     KOS 2007: Impact of novel agents in patients with poor prognosis myeloma defined by unfavorable cytogenetics, high age, and renal failure
  Heinz Ludwig, MD
Department of Medicine I
Center of Oncology and Hematology
Wilhelminenspital
Vienna, Austria
:
06.27.07     KOS 2007: International Staging System for Multiple Myeloma
  Philip Greipp, MD
Mayo Clinic
Internal Medicine
Rochester, Minnesota
06.27.07     KOS 2007: The Role of Thalidomide in Myeloma Patients Eligible for High-Dose Therapy
  Michele Cavo, MD
Seràgnoli Institute of Hematology and Medical Oncology
Bologna UniversitySchool of Medicine
Italy
06.27.07     KOS 2007: Role of Bortezomib in Myeloma Patients Eligible for High-Dose Therapy
  Sundar Jagannath, MD
St. Vincent's Comprehensive Cancer Center
New York, NY, USA
06.27.07     KOS 2007: The Role of Lenalidomide in Myeloma Patients Eligible for High Dose Therapy
  Vincent Rajkumar, MD
Division of Hematology
Mayo Clinic
Rochester, Minnesota, USA
06.27.07     KOS 2007: Frontline Treatment in Patients Not Eligible for Stem Cell Transplant
  Thierry Facon, MD
CHU
Lille, France
06.27.07     KOS 2007: Management of Toxicities from Novel Agents
  Mohamad Hussein, MD
Multiple Myeloma Clinical Research Clinical Director
H. Lee Moffitt Cancer & Research Institute
Tampa, Florida, USA
06.27.07     KOS 2007: Prognostic Factors for Multiple Myeloma in the Era of Novel Therapies
  Joan Bladé
Hematology Department
Institut of Hematology and Oncology
IDIBAPS, HospitalClínic
Barcelona, Spain
:
06.27.07     KOS 2007: Debate I - Should CR Achievement Be a Major Treatment Objective?
Introduction
  Raymond Alexanian, MD
06.27.07     KOS 2007: Debate I - Should CR Achievement Be a Major Treatment Objective? Yes!
  Jean Luc Harousseau, MD
Hôpital Hôtel Dieu
Nantes, France
06.27.07     KOS 2007: Debate I - Should CR Achievement Be a Major Treatment Objective? No!
  Mario Boccadoro, MD
Divisione di Ematologia dell’Università di Torino
Azienda Ospedaliera San Giovanni Battista
Torino, Italy

Includes questions and comments from the audience.
:
06.27.07     KOS 2007: Establishment of an Amyloid-Forming Human Cell Line
  Bonnie Arendt, MD
Dept. of Immunology
Mayo Cinic
Rochester, MN, USA
06.27.07     KOS 2007: Targeting Beta 1 Integrin Mediated Survival Signals in Multiple Myeloma
Lori Hazlehurst, PhD
Moffitt Cancer Center
Tampa, Florida, USA
06.27.07     KOS 2007: Response by SFLC and Marrow Flow Cytometry in MRC Myeloma IX
Roger Owen, MD
HMDS Laboratory and Department of Haematology
Leeds Teaching Hospitals
Leeds, UK
:
06.27.07     KOS 2007: Final Results of a Phase II PETHEMA Trial of Alternating Bortezomib and Dexamethasone as Induction Regimen Prior Autologous Stem Cell Transplantation (ASCT) in YOunger Patients with Multiple Myeloma (MM): Efficacy and Clinical Implications of Tumor Response Kinetics
  Laura Rosiñol, MD
Hospital Clinic
Barcelona, Spain
06.27.07     KOS 2007: Long-Term and Updated Results of the IFM99-03 and IFM99-04 ProtocolsComparing Autologous Followed by RIC-Allogeneic Transplantation and Double Transplant in High-Risk De Novo Multiple Myeloma
  Philippe Moreau, MD
on Behalf of the IFM Group
France
06.27.07     KOS 2007: Double versus Single Autologous Stem-Cell Transplantation for Multiple Myeloma: a Region Based Study in 485 patients from the Nordic Area
H.E. Johnsen, MD
Department of Hematology
Huddinge University Hospital
Sweden
06.27.07     KOS 2007: Prognostic impact of postransplantation complete remission (CR) in multiple myeloma(MM). Final results of a prospective study in a series of homogenously treated patients
Joaquin Martinez-Lopez
the Grupo Espanol de Mieloma (GEM)
Spain
:
06.28.07     KOS 2007: Drug Resistance in Myeloma
  W.S. Dalton, MD
H. Lee Moffitt Cancer Center and Research Institute
Tampa, Florida, USA
06.28.07     KOS 2007: AKT as a Therapeutic Target in Multiple Myeloma
  Noopur Raje, MD
Massachusetts General Hospital Cancer Center
Boston, MA, USA
06.28.07     KOS 2007: DNA Vaccines to Suppress Myeloma
  Freda Stevenson, MD
Molecular Immunology Group
Cancer Sciences Division
Tenovus Laboratory
Southampton University Hospitals Trust
Southampton, UK
06.28.07     KOS 2007: Novel Immunotherapy Strategies in Multiple Myeloma
  Nikhil Munshi, MD
Dana Farber Cancer Institute
Boston MA, USA
:
06.28.07     KOS 2007: Single VS Double Autologous Transplant
  Hartmut Goldschmidt, MD
Medizinischen Universitätsklinik und Poliklinik V
University of Heidelberg
Heidelberg, Germany
06.28.07     KOS 2007: Autologous Stem Cell Transplantation for MM: Analysis of Prognostic Factors
  Hermann Einsele, MD
Medizinische Klinik und Poliklinik I
Bayerische Julius-Maximilians-Universität Würzburg
06.28.07     Kos 2007: Allogeneic Transplantation in Multiple Myeloma
  Henk Lokhorst, MD
Dept. of Hematology
University Medical Center Utrecht, the Netherlands
06.28.07     KOS 2007: Donor lymphocyte infusion and other posttransplant Strategies After Allografting in Multiple Myeloma
  Nikolaus Kröger
Dept. of Stem Cell Transplantation
University Hospital Hamburg-Eppendorf, Germany
:
06.28.07     KOS 2007: Monoclonal Gammopathy of Undetermined Significance (MGUS) and Smoldering Multiple Myeloma (SMM)
  Robert A. Kyle, MD
Mayo Clinic
Rochester, MN, USA
06.28.07     KOS 2007: Solitary Bone and Extramedullary Plasmacytoma
  Raymond Alexanian, MD
M. D. Anderson Cancer Center
University of Texas
Houston, TX, USA

06.28.07     KOS 2007: AL Amyloidosis: Diagnosis and Prognosis
Giampaolo Merlini, MD
Amyloidosis Center
Fondazione IRCCS Policlinico San Matteo
University of Pavia
Pavia, Italy
06.28.07     KOS 2007: AL Amyloidosis: Response, Assessment, and Treatment
  Morie A. Gertz, MD
Mayo Clinic
Rochester, MN, U.S.A.
06.28.07     KOS 2007: The Role of High-Dose Therapy in AL-Amyloidosis
  Raymond Comenzo, MD
Hematology Service
Department of Medicine
Memorial Sloan-Kettering Cancer Center
New York, NY, USA
06.28.07     KOS 2007: Light Chain Deposition Disease
  Nelson Leung, MD
Mayo Clinic
Rochester, MN, USA
06.28.07     KOS 2007: What’s New About the POEMS Syndrome?
  Angela Dispenzieri, MD
Mayo Clinic Cancer Center
Rochester, MN, USA
06.28.07     KOS 2007: Paraproteinemia Related Neuropathies
Eduardo Nobile-Orazio, MD
Department of Neurological Sciences
Milan University
Milan, Italy
:
06.29.07     KOS 2007: High-Resolution Mapping of Common Gains and Losses in Myeloma
Jonathan Keats,MD
Mayo Clinic Comprehensive Cancer Center
Scottsdale, Arizona, USA
06.29.07     KOS 2007: Microchips for Optimized Fish Screening in Myeloma
Vincent Sieben
Department of Electrical & Computer Engineering
University of Alberta
Edmonton, Canada
06.29.07     KOS 2007: Gene Expression Profiles as Prognostic Factors for High-Dose Therapy and Bortezomib in Patients with Multiple Myeloma
Annemiek Broyl, MD
Department of Hematology
Erasmus Medical Center
Rotterdam, The Netherlands
06.29.07     KOS 2007: Cathepsin G is Upregulated in Patients Treated with IMIDS
  Suzanne Lentzsch, MD
University of Pittsburgh Cancer Institute
Pittsburgh, PA, USA
06.29.07     KOS 2007:Melphalan-Prednisone-Thalidomide (MP-T) is Also Superior to Melphalan-Prednisone (MP) in Patients 75 Years of Age or Older with Untreated Multiple Myeloma (MM). Preliminary Results of the Randomized, Double-Blind, Placebo Controlled IFM 01-01 Trial
Cyrille Hulin, MD
Itergroupe Francophone du Myélome
:
06.29.07     KOS 2007: Debate II - Should autologous transplant be part of the primary treatment in MM?
Introduction
Jean Luc Harousseau, MD
06.29.07     KOS 2007: Debate II - Should autologous transplant be part of the primary treatment in MM? NO
Jean-Paul Fermand, MD
Department of Immuno-Hematology
Hopital Saint-Louis, France
06.29.07     KOS 2007: Debate II - Should autologous transplant be part of the primary treatment in mm? YES
  Bart Barlogie, MD
Myeloma Institute for Research and Therapy
University of Arkansas for Medical Sciences
Little Rock, AR, USA
06.29.07     KOS 2007: Debate II - Should autologous transplant be part of the primary treatment in MM?
Q & A
Questions from Dr. Harousseau and the audience.
:
06.29.07     KOS 2007: The Importance of New and Evolving Response Criteria
  Brian G.M. Durie, MD
Samuel Oschin Comprehensive Cancer Institute
Cedars Sinai Medical Center
Los Angeles, CA, USA
06.29.07     KOS 2007: Individualizing Treatment in the Area of Multiple Novel Agents
  Jesús San Miguel, MD
Hospital Clinico Universitario
Universidad de Salamanca
Salamanca, Spain
06.29.07     KOS 2007: European Myeloma Network: The Present and the Future
  Pieter Sonneveld
The European Myeloma Network (EMN)
06.29.07     KOS 2007: Future Perspectives in the Management of Myeloma
  Kenneth C. Anderson, MD
Dana-Farber Cancer Institute
Boston, MA, USA

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