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ASH 2005 Webcast

The IMF is pleased to provide you with a broad sampling of myeloma presentations and posters from the 2005 annual meeting of the American Society of Hematology in San Diego, California. We hope you will find this material informative and useful.

ASH 2005 Presentations and Posters
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Velcade (Bortezamib)
Update On The Velcade APEX Trial For Relapsed Myeloma
Dr. Paul Richardson of the Dana Farber Cancer Institute provides an update on the Velcade APEX trial

Update On Neuropathy In Patients On The Velcade APEX Trial
Dr. San Miguel presented data on the rate of peripheral neuropathy in the APEX Velcade trial

Frontline Therapy With Velcade
Dr. Jagannath’s reports on a multi-center trial for newly diagnosed myeloma patients receiving frontline therapy with Velcade

Combination Therapy With Melphalan and Velcade
Dr. Cavenagh presented results of a trial combining Velcade with another chemotherapy agent, melphalan, in patients with relapsed/refractory disease

Melphalan, prednisone, and Velcade In Previously Untreated Elderly Patients
Dr. San Miguel presented interim data on the ongoing PETHEMA study of melphalan, prednisone, and Velcade in elderly, previously untreated myeloma patients

Combination Therapy With Velcade, Adriamycin and Dexamethason (PAD)
Dr. Cavenagh reported on his ongoing trial combining Velcade, Adriamycin, and dexamethasone (PAD) in previously untreated myeloma

Prophylaxis For Herpes Zoster (Shingles) With Velcade Therapy
Dr. Vij addressed the increased incidence of herpes zoster (shingles) with Velcade in the peri-transplant setting and preventative measures that can be taken to avoid this complication

Revlimid (Lenalidomide)
Combination Therapy With Melphalan, Prednisone and Revlimid
Dr. Palumbo reported on the results of a Phase II trial of melphalan/prednisone/revlimid

Thalomid (Thalidomide)
Combination Therapy With Thalidomide And Dexamethasone In Elderly Patients
Dr. Ludwig presented an interim analysis of an ongoing trial of thal/dex versus MP in 205 elderly (median age 72), newly diagnosed patients with myeloma

Combination Therapy With Melphalan, Prednisone and Thalidomide
Dr. Facon reports on an interim analysis of the ongoing Intergroup Francais du Myelome (IFN) 99-06 clinical trial comparing melphalan–prednisone (MP), melphalan-prednisone-thalidomide (MPT), and stem cell transplant with reduced-dose-chemotherapy (melphalan 100 mg/m2 or “mel 100”) in elderly (65-75 years of age), newly diagnosed myeloma patients

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