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ASH 2005 Webcast

The IMF is pleased to provide you with a broad sampling of myeloma presentations and posters from the 2005 annual meeting of the American Society of Hematology in San Diego, California. We hope you will find this material informative and useful.

ASH 2005 Presentations and Posters
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Thalomid (Thalidomide)
Combination Therapy With Melphalan, Prednisone and Thalidomide
Dr. Palumbo began presents results a trial of melphalan/prednisone/thalidomide (MPT)for myeloma patients over 65 years if age

Gene Expression In Patients Treated With Thal/Dex
Dr. Kumar presented the results of a gene expression study conducted on patients who were randomized to receive either thalidomide and dexamethasone

Novel Agent Combinations
Combination Therapy With Thalidomide, Velcade And Dexamethasone
Dr. Wang presented interim results of a study of combination therapy with Thalidomide, Velcade and Dexamethasone in newly-diagnosed myeloma patients

Therapy With Velcade And The Radiopharmaceutical Quadramet
Dr. Dispenzieri presented data on a pre-clinical mouse study with the combination of Velcade and the radiopharmaceutical Quadramet (153 samarium EDTMP)

Combination Therapy With Revlimid and Velcade
Dr. Richardson also presented early data on the Phase I Revlimid + Velcade trial for relapsed and refractory myeloma

New Agents
Aplidin For Relapsed/Refractory Myeloma
Dr. San Miguel presented preliminary data from a Phase I/II study in patients with relapsed/refractory myeloma of the novel therapy Aplidin, which is a marine-derived molecule with a novel mechanism of action

Phase I Trial Of Atipromod
Dr. Wang presented data on a Phase I dose escalation multi-center clinical trial with the new drug Atiprimod for patients with relapsed/refractory myeloma

Stem Cell Mobilization With AMD-3100
Dr. McGuirk reported on the first 70 patients enrolled in the AMD-3100 compassionate use program for poor stem cell mobilizers in need of stem cell harvest prior to autologous stem cell transplantation (SCT)

Transplantation
Stem Cell Harvesting Using GCSF Alone
Dr. Vij presented the results of a trial using GCSF alone in successful mobilization of stem cells

Molecular Biology and Genetics, Other Research
Overview Of The IMF's Bank On A Cure Program
Dr. Van Ness presented his current work with the IMF Bank On A Cure program’s genetic data along with information about current and future research being conducted by the Bank On A Cure Team

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