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Recognizing and Addressing the Side Effects of Treatment


Osteonecrosis of the jaw is a condition whereby there is loss or destruction of the bone underneath the teeth. This loss of bone appears to be caused by a combination of poor blood supply and impaired bone remodeling or healing.

Osteonecrosis of the Jaw

Special Advisory: Osteonecrosis of the Jaw

Use of Bisphosphonates in Multiple Myeloma: IMWG Response to Mayo Clinic Consensus Statement
Published in the Mayo Clinic Proceedings 2007;82:516-522

Wall Street Journal Article On Osteonecrosis Of The Jaws
You can also read a Wall Street Journal article that discusses this issue and includes a quote from Dr. Durie

Aredia/Zometa and osteonecrosis of the jaws

Food and Drug Administration (FDA) MedWatch Postings About Osteonecrosis Of The Jaw
FDA and Novartis notified healthcare professionals of revisions the PRECAUTIONS and ADVERSE REACTIONS sections of labeling for Aredia and Zometa