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Understanding Treatment of Myeloma-Induced Vertebral Compression Fractures
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Up to 90% of myeloma patients develop bone lesions during the course of their dis­ease; 70% have bone loss in the spine. A vertebral compression fractures (VCF) occurs when the vertebra fractures or collapses because the bone is too weak to withstand the pressure or stress placed upon it. With multiple fractures, the spine shortens and becomes misaligned, causing a curvature of the spine known as “kypho­sis.” Pain occurs both suddenly, as a result of the movement of the fracture fragments, and often secondarily, as a result of the deformity, causing a chronic dull ache in the facet joint of the vertebra. As treatment for myeloma improves and myeloma patients live longer, it is especially impor­tant to reduce the pain and disability that can result from VCFs. This IMF booklet describes how to manage this painful problem. 

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