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THE INTERNATIONAL MYELOMA FOUNDATION SAYS ECOG RESULTS COULD IMPROVE SURVIVAL WHILE REDUCING SIDE EFFECTS FOR MANY PATIENTS
Findings Challenge Traditional Assumption that More-Is-Better when Treating Cancer
04.04.07

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National Cancer Institute Press Release: Low-dose Steroid Combined with Lenalidomide Prolongs Survival Compared with High-dose Steroid for Multiple Myeloma Treatment
Mayo Clinic Press Release: Multiple Myeloma Clinical Trial Closes Early Due to Superior Results of Comparative Treatment
Celgene Press Release: ECOG Phase III Newly Diagnosed Multiple Myeloma Trial (E4A03) Reports LENALIDOMIDE Plus Low-Dose Dexamethasone Suggests Survival Advantage for Patients with Multiple Myeloma
Abstract: Phase III trial of lenalidomide plus high-dose dexamethasone compared to lenalidomide plus low-dose dexamethasone in newly diagnosed multiple myeloma
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National Institute Of Health Release: Low-dose Steroid Combined with Lenalidomide Prolongs Survival Compared with High-dose Steroid for Multiple Myeloma Treatment


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National Cancer Institute Press Release: Low-dose Steroid Combined with Lenalidomide Prolongs Survival Compared with High-dose Steroid for Multiple Myeloma Treatment

Mayo Clinic Press Release: Multiple Myeloma Clinical Trial Closes Early Due to Superior Results of Comparative Treatment
Mayo Clinic Cancer Center announced today that a multiple myeloma clinical trial has shown a significant improvement in survival with lenalidomide plus low-dose dexamethasone therapy compared to lenalidomide plus high-dose dexamethasone.

Celgene Press Release: ECOG Phase III Newly Diagnosed Multiple Myeloma Trial (E4A03) Reports LENALIDOMIDE Plus Low-Dose Dexamethasone Suggests Survival Advantage for Patients with Multiple Myeloma

Abstract: Phase III trial of lenalidomide plus high-dose dexamethasone compared to lenalidomide plus low-dose dexamethasone in newly diagnosed multiple myeloma
(E4A03): A trial coordinated by the Eastern Cooperative Oncology Group.
S. V. Rajkumar, S. Jacobus, N. Callander, R. Fonseca, D. Vesole, M. Williams, R. Abonour, D. Siegel, P. Greipp

Understanding Revlimid®
Learn more about Revlimid® (lenalidomide), approved by the FDA for use in myeloma.

Understanding Thalidomide Therapy
Using thalidomide to treat myeloma is a new idea, but thalidomide itself has been studied for many decades.

Understanding Dexamethasone and Other Steroids
What dexamethasone is, how it works, possible side effects, and more.

National Institute Of Health Release: Low-dose Steroid Combined with Lenalidomide Prolongs Survival Compared with High-dose Steroid for Multiple Myeloma Treatment
The clinical trial was sponsored by the National Cancer Institute (NCI), part of the National Institutes of Health, and conducted by a network of researchers led by the Eastern Cooperative Oncology Group (ECOG).