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February 14, 2002: IMF Myeloma Minute
02.14.02
Myeloma Items of Interest:

Hi-dose chemo no benefit in MM
(From Hem/Onc Today)
High-dose chemotherapy with stem cell rescue may not be the best therapy for patients with multiple myeloma, according to a trial presented here at the 43rd Annual Meeting of ASH. Spanish investigators found that although the standard approach increased complete responses, it did not significantly affect progression-free or overall survival.


Research Updates:

The following research updates have been published in the February 15, 2002 issue of Blood.

Negative regulation of erythroblast maturation by Fas-L+/TRAIL+ highly malignant plasma cells: a major pathogenetic mechanism of anemia in multiple myeloma.

CD40 activation induces p53-dependent vascular endothelial growth factor secretion in human multiple myeloma cells.

Cell surface proteoglycan syndecan-1 mediates hepatocyte growth factor binding and promotes Met signaling in multiple myeloma.


What's New at the IMF:

IMF Patient & Family Seminar
Don't miss the IMF's upcoming
Atlanta Patient & Family Seminar, March 8th and 9th at the Atlanta Marriott Marquis Hotel. Patient & Family Seminars are the best way to stay informed of new developments in the treatment and management of myeloma. Patients & Family Seminars are extremely valuable for both newly-diagnosed patients as well as long-term survivors. The myeloma world is rapidly changing and attending a seminar is a great way to stay "in the loop." Knowledge is power! The more you learn about myeloma, the easier it will be to make educated treatment choices. You may register online or by calling the IMF at (800) 452-CURE.

2001 Year-End Issue of Myeloma Today Available Online
Check out the latest issue of this informative newsletter. Myeloma Today is a "must read" for everyone with an interest in multiple myeloma!


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