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January 10, 2002: IMF Myeloma Minute
01.10.02

Research Updates:

How myeloma lyses bone
Blood, 15 December 2001

Myeloma cells induce imbalance in the osteoprotegerin/osteoprotegerin ligand system in the human bone marrow environment.
Blood, 15 December 2001

Cyclosporin A combined with vincristine, doxorubicin and dexamethasone (VAD) compared with VAD alone in patients with advanced refractory multiple myeloma: an EORTC–HOVON randomized phase III study.
British Journal of Haematology

Thalidomide in refractory and relapsing multiple myeloma.
Semin Oncol 2001 Dec.

Stem Cell Transplant Patients Die Sooner if Depressed
(Courtesy of Acurian.com)

Mayo Clinic Study Shows Thalidomide Significantly Affects Early-stage Multiple Myeloma
(Courtesy of Acurian.com)


Clinical Trials:

Phase I Study of 2-Methoxyestradiol in Patients With Advanced Solid Tumors

Phase II Study of Autologous Peripheral Blood Stem Cell (PBSC) Transplantation Followed By Non-Myeloablative PBSC Transplantation in Patients With Multiple Myeloma

Phase III Randomized Study of Doxorubicin, Dexamethasone, and High-Dose Melphalan With or Without Thalidomide in Patients With Multiple Myeloma

These clinical trials were added to the NCI's database in January 2002. For a comprehensive listing of ongoing clinical trials available to myeloma patients, please visit the IMF's clinical trials page. Interested in learning more about clinical trials? Visit the NCI's Understanding Trials page for informative answers to common questions about clinical trials.


IMF News:

Are You Reading Myeloma Today?
Myeloma Today is the official newsletter of the IMF. Published six-times-per-year, Myeloma Today is available free-of-charge, by subscription, and is an excellent way to stay abreast of the latest developments in the treatment and management of multiple myeloma. Knowledge is power! The more you know, the easier it will be to make educated treatment choices. Both electronic and print subscriptions are available. Why wait? Sign up today!

The IMF is Only a Phone Call Away!
Have a question about multiple myeloma? Trying to find a myeloma specialist in your area? Looking for a local myeloma support group? The IMF can help! Our experienced, caring staff is ready to assist you in any way that we can. Just call
(800) 452-CURE. (Toll-free hotline available within the US and Canada - others, please call 818-487-7455.)

Please Help Us Help Others
As a non-profit organization, we depend on the generosity of members like yourself. Your support insures that, among other things, a much-needed IMF Info Pack will arrive in the mailbox of a newly-diagnosed patient; that Patient & Family Seminars will continue to provide you with a panel of world-renowned myeloma specialists from whom to learn about the latest findings; and that myeloma research will continue to advance, aimed at discovering the ultimate answer - a cure for myeloma. The IMF is about People Helping People. We are all in this fight together, struggling each and every day with an enemy that we cannot see. We ask that you lend a hand to help us help others by making a tax-deductible donation. Donations in honor of a birthday, anniversary or other special occasion make a wonderful gift and are a special way to show your support of the myeloma community. On behalf of our more than 80,000 members, we sincerely thank you for your support.


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