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Understanding ZIO-101
(Darinaparsin)
Darinaparsin is a novel, organic arsenic that kills human myeloma cell lines grown in the laboratory. It is also active against human myelomas that have been transplanted into mice. As a form of organic arsenic, Darinaparsin represents a new class of small molecule cancer therapy.
07.19.07

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Darinaparsin (S-dimethylarsino-glutathione)is a novel, organic arsenic. Darinaparsin kills human myeloma cell lines grown in the laboratory. Darinaparsin is also active against human myelomas that have been transplanted into mice. Arsenic has been used in its inorganic form to treat various diseases for over 2000 years, even though it has been associated with undesirable side effects. As a form of organic arsenic, Darinaparsin represents a new class of small molecule cancer therapy.


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