- Medicare Chief Wants Deadline to Be Kept
Despite a call for an extension from some lawmakers, the nation's chief Medicare official says the government should stick to the May 15 deadline for people to enroll for the new prescription drug benefit because it will force them to act. (from the Associated Press by way of the Seattle Post Intelligencer)
Medicare Deadline Reminder.
- Feedback Project at Little Rock Focuses On Patients' Needs
"This idea is where the future of medicine is heading," says Dr. Charles Smith, UAMS' medical director, who expects similar projects to be utilized in all UAMS clinics in the near future. "The doctor-patient encounter is becoming demystified. This will provide us with guidance on how the system needs to change and make it more sensitive to patient needs." (from PRWeb)
- Internet Research Builds Cancer Patients’ Confidence
Research shows strong parallels between Internet use and the patients’ feelings about their treatment. Those who used the Internet and those who received Internet information from family members or friends were more likely to view their relationship with their doctors as a partnership, and were more comfortable asking questions and challenging treatment alternatives. Read entire study in PDF form. (from Newswise)
- Don't wait, or you will miss Multiple Strategies for Treating Myeloma: Case Discussions
March 30, 2006
Fort Lauderdale, Florida
Register now for this case-based CME dinner activity for physicians. Jointly sponsored by the IMF and the Institute for Continuing Healthcare Education.
WHAT'S NEW IN RESEARCH
(IMF Scientific Advisors are marked with asterisks)
- Proteasome inhibitors induce a terminal unfolded protein response in multiple myeloma cells
Esther A Obeng, Louise M Carlson, Delia M Gutman, William J Harrington, Jr., Kelvin P Lee, and Lawrence H Boise
Blood published 28 February 2006, 10.1182/blood-2005-08-3531
- Bortezomib mediates antiangiogenesis in multiple myeloma via direct and indirect effects on endothelial cells.
Roccaro AM, Hideshima T, Raje N, Kumar S, Ishitsuka K, Yasui H, Shiraishi N, Ribatti D, Nico B, Vacca A, Dammacco F, Richardson PG*, Anderson KC*.
Cancer Res. 2006 Jan 1;66(1):184-91.
- Immunomodulatory drug lenalidomide (CC-5013, IMiD3) augments anti-CD40 SGN-40-induced cytotoxicity in human multiple myeloma: clinical implications.
Tai YT, Li XF, Catley L, Coffey R, Breitkreutz I, Bae J, Song W, Podar K, Hideshima T, Chauhan D, Schlossman R, Richardson P*, Treon SP, Grewal IS, Munshi NC, Anderson KC*.
Cancer Res. 2005 Dec 15;65(24):11712-20.
- Immunomodulatory analogues of thalidomide in the treatment of multiple myeloma.
Suppiah R, Srkalovic JG, Hussein MA.
Clin Lymphoma Myeloma. 2006 Jan;6(4):301-5.
- Adenoviral-mediated transfer of human wild-type p53, GM-CSF and B7-1 genes results in growth suppression and autologous anti-tumor cytotoxicity of multiple myeloma cells in vitro.
Ren SP, Wu CT, Huang WR, Lu ZZ, Jia XX, Wang L, Lao MF, Wang LS.
Cancer Immunol Immunother. 2006 Apr;55(4):375-85. Epub 2005 Jul 2.
- Treatment of Bendamustine and Prednisone in patients with newly diagnosed multiple myeloma results in superior complete response rate, prolonged time to treatment failure and improved quality of life compared to treatment with Melphalan and Prednisone-a randomized phase III study of the East German Study Group of Hematology and Oncology (OSHO).
Ponisch W, Mitrou PS, Merkle K, Herold M, Assmann M, Wilhelm G, Dachselt K, Richter P, Schirmer V, Schulze A, Subert R, Harksel B, Grobe N, Stelzer E, Schulze M, Bittrich A, Freund M, Pasold R, Friedrich T, Helbig W, Niederwieser D.
J Cancer Res Clin Oncol. 2006 Apr;132(4):205-12. Epub 2006 Jan 10.
- Resveratrol induces apoptosis of human malignant B cells by activation of caspase-3 and p38 MAP kinase pathways.
Shimizu T, Nakazato T, Xian MJ, Sagawa M, Ikeda Y, Kizaki M.
Biochem Pharmacol. 2006 Mar 14;71(6):742-50. Epub 2006 Jan 19.
- Circulating fragmented nucleosomal DNA and caspase-3 mRNA in patients with lymphoma and myeloma.
Deligezer U, Erten N, Akisik EE, Dalay N.
Exp Mol Pathol. 2006 Feb;80(1):72-6. Epub 2005 Jun 15.
If you would like more information about any clinical trial, you can call the IMF Hotline at 800-452-CURE. The Myeloma
Matrix has a current list of all myeloma trials from
pre-clinical to recently FDA approved. If you would like to browse trials
currently open for enrollment, visit the Clinical Trials page of
the IMF web site. Among the links, you will find EmergingMed,
with whom the IMF has entered into a partnership to assist you in matching
trials to your particular patient profile (i.e., stage of disease,
previous treatment, how well you are able to carry out the activities of
daily living, etc.) and by doing so, increase your chances of being
eligible. You can also learn more about clinical trials by reviewing
materials from the National
UPCOMING SEMINARS AND CLINICAL
||Focus on Myeloma and Plasma Cell Disorders
March 24-25, 2006
Lauderdale Patient & Family Seminar|
March 31 -
April 1, 2006
Fort Lauderdale, Florida
||Seoul Patient & Family Seminar
April 8, 2006
Seoul, South Korea
||Seoul Multiple Myeloma Symposium
April 8, 2006
Seoul, South Korea
||Vienna Patient & Family Seminar
May 5-6, 2006
Patient & Family Seminar|
Patient & Family Seminar|
The IMF's comprehensive "How-to-FUNdraise" guide is what you need if you're thinking about fundraising in your community but don't know where to start. The guide contains the A - Z of fundraising ideas--like running in a local marathon and asking for donations per mile for myeloma; having a summer BBQ, where you charge a cover and hold a raffle; asking your local supermarket to donate wine and cheese, then selling tickets and having a cocktail party--as well as tips and guidelines for success. Check out the FUNdraisers below:
Annual Robert A. Kyle Lifetime Achievement Award to go to Brian Durie,
May 16, 2006
Dr. Durie is being honored for his extensive body of work, much of it focused on the proper assessment of patients to ensure they receive the most effective care. Dr. Durie co-created the Durie/Salmon Myeloma Staging System, the first system ever developed to classify myeloma in a standard, universal fashion, and the vital building block for the International Staging System, also co-developed by Dr. Durie with the International Working Group. In total, Dr. Durie has written over 400 research papers, sixteen book chapters, and five books--work which has had an impact on myeloma treatment around the world.
In Canada, Sheldon is going to run 1000 kilometers to raise
money to support myeloma research.
||Music Against Myeloma
April 5th, 2006
New York, New York
||I° Memorial Schirinzi Augusto Mario IMF
Saturday, April 22, 2006
Ferrizzi Golf Tournament|
May 20 2006
Annual JC Golf Tournament|
May 20, 2006
Cravotta Golf Tournament|
May 20, 2006
||Terry DuBois’ Birthday Bash for Myeloma
June 10, 2006
Annual Multiple Musicians Against Multiple
July 9, 2006
for the Cure Extended
Many of you requested envelopes to participate in our
Mail For The Cure campaign, but were unable to send them out by
the end of the year. So we have decided to extend the program for
another six months. So far, the campaign has raised over $8,000 to
support the IMF's programs, and we know there will be a lot more coming
in judging by your requests for information. If you have any questions
or would like more envelopes and/or a letter template, please contact
Suzanne Battaglia at SBattaglia@myeloma.org or at
The IMF's comprehensive "How-to-FUNdraise"
guide is what you need if you're thinking about fundraising in your
community, but don't know where to start. The guide will give you the "A
to Z" of fundraising ideas, and other helpful
Shop at leading internet retailers (e-tailers) like Amazon.com, and they will donate a portion of your
purchase to the IMF. You pay no more than you would normally for
everything from clothing to computers to cruises. Whatever you buy, the
programs, publications and research supported by the IMF will
Visit our Shop for the IMF page at http://shop.myeloma.org to see the complete list of
popular etailers who will donate a portion of your purchase to the IMF.
Giving has never been more painless!
Wearing ribbons has become a wonderful way for people to show their support for patients and family members coping with cancer and other diseases. The IMF's Multiple Myeloma Ribbon of Hope lets people know you care and calls attention to the need for action to find a cure. You can obtain your Ribbon of Hope by making a tax-deductible contribution of $5 or more. Order them on the web.
Imagine Moving Forward is the theme of the IMF's popular myeloma bracelet. At medical
conferences and patient & family seminars we see people wearing them
in honor, celebration, or in memory of a loved one. They're only $1 each
in sets of 10, so order them for everyone you know who has been touched by
myeloma. Order them on the web. If you have questions about the
bracelets or would like more information, contact Suzanne Battaglia at
(800) 452-2873, ext. 227, or SBattaglia@myeloma.org.
See more exciting ways to help the IMF
continue its important work in education, support and
Help Us Help Others...
As a non-profit organization, the
IMF is completely dependent on the support of our members. Tax-deductible
donations in honor of a friend or family member make great gifts and are a
wonderful way to celebrate a special occasion. You can donate
online or by calling the IMF at (800) 452-CURE. We sincerely thank you
for your support.