- We have been very busy!
In the last couple of months, Patient & Family Seminars were held in Spain, Italy, France, Germany, and Turkey. These seminars were very successful, drawing hundreds of attendees and the top talent in myeloma from the countries in which they were held. Here are the first of the reports:
- New! Hand Printed Holiday Cards!
This holiday season, send a hand made holiday card, printed one at a time by IMFer Kathleen Tezla and her father, myeloma patient Joseph, on fine art watercolor paper using an antique printing press. The result is a deeply embossed design, archival in quality so that these stories can be remembered and passed on for many more holiday seasons to come.
Lights, Camera, Action, Cure!
15th Anniversary Ribbon of Hope Gala
November 12, 2005
Anyone who has ever contacted the IMF knows that every day we are dedicated to helping the community of myeloma patients, their caregivers, their physicians and nurses, and the researchers who work tirelessly to find a cure. The IMF is proud of the patient and family seminars we put on all over the world, the intelligent, informed staffers on our hotline, the thousands of publications we provide free of charge, and the groundbreaking research we fund. But as a non-profit, we take nothing for granted. We know that none of this work is possible without your generous support.
The Ribbon of Hope Gala is the IMF's big annual fundraiser. At the Gala we raise money to help pay for everything we do, from Info Packs to Bank On A Cure®. And we honor those whose work makes a difference to us all.
This year's individual honoree is Dr. David Agus of Cedar's Sinai Medical Center. Dr. Agus' research in proteomics reveals valuable information regarding "on" and "off" switches of cancer and ultimately a more complete understanding of the various factors that influence cancer.
This year's corporate honoree is Affymetrix, a pioneer in creating breakthrough tools for genomic research. The machines produced by Affymetrix are the cornerstone of the IMF's Bank On A Cure program, providing the tools to process myeloma patients' DNA.
The IMF wishes to thank the individuals and companies who have so generously sponsored the Gala, making it possible for all monies raised to go directly to the programs of the IMF.
- Darlene and Walter Reinhold
- Wendy Breslow
- Barbara & Alvin Dischler
- John Glover
- Carol & Benson Klein
- Sharon & Chuck Newman
- Catherine Olim
- Françoise Pransky
- Jeri Ryan
- Dr. and Mrs. Alan M. Weinstein
- Teri & Sigmond Abelson
- Herman Adler
- Luanne and John Baker
- Prudy and David Brown
- Booz Allen Hamilton, Inc.
- Michael Carreon
- Cedars-Sinai Medical Center
- Louise and Frank Chut
- Shelley Cohen
- Elizabeth & Charles-Daniel Dahan
- Aldo Del Col
- Barbara & Alvin Dischler
- Eli Broad Foundation
- Jan & Robert Fenton
- Paula Fischer
- The Five G’s Family Foundation
- Ira Freeman
- Stephanie Gallagher
- Harvey S. Gilbert
- Merv Griffin
- Murray P. Hayutin
- Lori Klein
- Linda and Lew Kairys
- Trudy and Al Kallis
- Dorita and Alvin Kaufman
- Carol and Benson Klein
- Roberta and Ray Klein
- Adrienne and Martin Levine
- Doug Lewis
- Millennium Pharmaceuticals
- Françoise Pransky
- Sharon and Charles Newman,
- North Texas Myeloma Support Group
- Darlene and Walter Reinhold
- John S. Rogers
- Joyce and Carl Rudnick
- San Diego Support Group
- Judy G. Schwartz
- Carrie and David Sears
- Diane and Jarvis Seccombe
- Susan and Eric Smidt
- Taffy Stern
- Francine Trattner
- Jodi and Brian Van Ness
- Vista Com
- James R. Walsh
- Marcia Webber
- Steve Weiss
WHAT'S NEW IN RESEARCH
- Bisphosphonate-induced exposed bone (osteonecrosis/osteopetrosis) of the jaws: risk factors, recognition, prevention, and treatment.
Marx RE, Sawatari Y, Fortin M, Broumand V.
J Oral Maxillofac Surg. 2005 Nov;63(11):1567-75
- Resveratrol Inhibits Myeloma Cell Growth, Prevents Osteoclast Formation, and Promotes Osteoblast Differentiation
Boissy P, et al
Cancer Research 65, 9943-9952, November 1, 2005
Resveratrol, a polyphenol found most notably in grapes and red wine, can help thwart bone marrow cancer myeloma
- Excessive fluid accumulation during stem cell mobilization: a novel prognostic factor of first-year survival after stem cell transplantation in AL amyloidosis patients
Nelson Leung, Tessa R. Leung, Stephen S. Cha, Angela Dispenzieri, Martha Q. Lacy, and IMF Scientific Advisor Morie A. Gertz
Blood 2005;106 3353-3357
- Induction of HM1.24 peptide-specific cytotoxic T lymphocytes by using peripheral-blood stem-cell harvests in patients with multiple myeloma
Jalili A. et al
Blood 2005;106 3538-3545
- Relationship of patient survival and chromosome anomalies detected in metaphase and/or interphase cells at diagnosis of myeloma
Gordon W. Dewald, Terry Therneau, Dirk Larson, You Kyoung Lee, Stephanie Fink, Stephanie Smoley, Sarah Paternoster, Adewale Adeyinka, Rhett Ketterling, Daniel L. Van Dyke, IMF Scientific Advisors Rafael Fonseca, and Robert Kyle
Blood 2005;106 3553-3558
- PK11195, a peripheral benzodiazepine receptor (pBR) ligand, broadly blocks drug efflux to chemosensitize leukemia and myeloma cells by a pBR-independent, direct transporter-modulating mechanism
Walter R, et al
Blood 2005;106 3584-3593
- Nongenotoxic activation of the p53 pathway as a therapeutic strategy for multiple myeloma
Stuhmer T, et al
Blood 2005;106 3609-3617
- Sequential, cycling maintenance therapy for post transplant multiple myeloma.
Chen CI, Nanji S, Prabhu A, Beheshti R, Yi QL, Sutton D, IMF Scientific Advisor Stewart AK.
Bone Marrow Transplant. 2005 Oct 24; [Epub ahead of print]
- Progress in hematopoietic stem cell transplantation in multiple myeloma.
IMF Scientific Advisor Gahrton G.
Curr Opin Hematol. 2005 Nov;12(6):463-70.
- Total Soluble HLA Class I and Soluble HLA-G in Multiple Myeloma and Monoclonal Gammopathy of Undetermined Significance.
Leleu X, Le Friec G, Facon T, Amiot L, Fauchet R, Hennache B, Coiteux V, Yakoub-Agha I, Dubucquoi S, IMF Scientific Advisor Avet-Loiseau H, Mathiot C, IMF Scientific Advisor Bataille R, Mary JY.
Clin Cancer Res. 2005 Oct 15;11(20):7297-303.
- Re-use of the original infusional induction chemotherapy as salvage therapy in myeloma patients relapsing after one autograft.
Sirohi B, IMF Scientific Advisor Powles R, Rudin C, IMF Scientific Advisor Singhal S, Kulkarni S, Saso R, Horton C, IMF Scientific Advisor Mehta J, Treleaven J.
Hematology. 2005 Oct;10(5):361-4.
- Human myeloma cells express the bone regulating gene Runx2/Cbfa1 and produce osteopontin that is involved in angiogenesis in multiple myeloma patients.
Colla S, Morandi F, Lazzaretti M, Rizzato R, Lunghi P, Bonomini S, Mancini C, Pedrazzoni M, Crugnola M, Rizzoli V, Giuliani N.
Leukemia. 2005 Oct 6; [Epub ahead of print]
- CLINICAL TRIALS
If you would like more information about any clinical trial, you can call the IMF Hotline at 800-452-CURE. The Myeloma Matrix has a current list of all myeloma trials from pre-clinical to recently FDA approved. If you would like to browse trials currently open for enrollment, visit the Clinical Trials page of the IMF web site. Among the links, you will find EmergingMed, with whom the IMF has entered into a partnership to assist you in matching trials to your particular patient profile (i.e., stage of disease, previous treatment, how well you are able to carry out the activities of daily living, etc.) and by doing so, increase your chances of being eligible. You can also learn more about clinical trials by reviewing materials from the National Cancer Institute.
UPCOMING EVENTS AND EXCITING OPPORTUNITIES
The IMF's comprehensive "How-to-FUNdraise" guide is what you need if you're thinking about fundraising in your community, but don't know where to start. The guide will give you the "A to Z" of fundraising ideas, and other helpful suggestions.
See complete list of UPCOMING EVENTS.
SHOP FOR THE IMF
Shopping for the Holidays and the Cure
Yes, it's that time of year, when we're all looking at the calendar and counting up how many more shopping days we have left until Christmas or Hannukah. Here's a way to make your already busy life less hectic. All you have to do is click on the "Helping the IMF" tab at (www.myeloma.org) and order just the gift you want. On the left side you will see a heading called "Shop For The IMF" and there you will find the retailers you would probably buy from anyway, such as Barnes & Noble, Amazon.com, buy.com, FTD.com and
1-800-Flowers.com (for decorating those festive holiday tables), Lands' End, Macy's, Sharper Image and Walmart, to name a few. The IMF receives a portion of everything you buy when you access their site via special links we have set up, so not only are you saving money on gas by not driving from store to store, you're helping to raise money for myeloma too. Or click on either the "Events" or "Helping the IMF" tabs and scroll down through the items that are designed by our IMFers, such as the new hand printed holiday cards by Kathleen Tezla, Pam Larsen's Multiple Colors For Multiple Myeloma, beautiful personalized keychains and earrings, or Kristi Difford's gorgeous personalized jewelry. There are also scenic cards designed by Irma Catlett for the IMF and Cathy Goetz's wine bottle vests for dressing up that holiday dinner gift of wine. And of course, there are the multiple myeloma wrist bands, which you can tie into your package ribbons, and the Ribbon of Hope pin for giving the gift of hope. And all from the comfort of your laptop! So start early – avoid the crowds – and be the first in your neighborhood to cross all those items off your list.
Multiple Colors for Multiple Myeloma Keychains and Earrings
The gift-giving holidays will be upon us sooner than we think. And there are always birthdays, anniversaries, and "just because you're you" occasions. Here are two new items to help support the International Myeloma Foundation: colorful keychains and chandelier earrings of Swarovski crystals.
Imagine Moving Forward is the theme of the IMF's popular myeloma bracelet. At medical conferences and patient & family seminars we see people wearing them in honor, celebration, or in memory of a loved one. They're only $1 each in sets of 10, so order them for everyone you know who has been touched by myeloma. Order them on the web. If you have questions about the bracelets or would like more information, contact Suzanne Battaglia at (800) 452-2873, ext. 227, or SBattaglia@myeloma.org.
Multiple Myeloma Awareness Jewelry
The response has been great for the new garnet bracelet IMFer Kristi Difford has added to her line of beautiful custom bracelets to honor those who have joined the struggle against multiple myeloma. Check it out.
See more exciting ways to help the IMF continue its important work in education, support and research.
ITEMS OF INTEREST
The HealthWell Foundation has recently opened the Multiple Myeloma fund to help even more patients gain access to the best health care available. You can contact them at (800) 675-8416 or at www.healthwellfoundation.org.
- Patient Access Network Foundation (PANF) provides copay assistance for myeloma. Thalomid is the MRDD product covered for this condition. The PANF formerly just covered qualified myeloma patients_ erythropoietin alpha expenses. Patients or healthcare providers may initiate the application process. Applications must be completed by both physician and patient, and income verification is required. Their phone number is 1-866-316-7263.
|Help Us Help Others...|
As a non-profit organization, the IMF is completely dependent on the support of our members. Tax-deductible donations in honor of a friend or family member make great gifts and are a wonderful way to celebrate a special occasion. You can donate online or by calling the IMF at (800) 452-CURE. We sincerely thank you for your support.