WHAT'S NEW IN RESEARCH
- IGF-1 receptor tyrosine kinase inhibition by the cyclolignan PPP induces G2/M-phase accumulation and apoptosis in multiple myeloma cells
Stromberg T, et al
Blood published 15 September 2005, 10.1182/blood-2005-01-0306
- Circulating plasma cells detected by flow cytometry as a predictor of survival in 302 patients with newly diagnosed multiple myeloma
Nowakowski G, et al
Blood 2005;106 2276-2279
- Myeloma cells block RUNX2/CBFA1 activity in human bone marrow osteoblast progenitors and inhibit osteoblast formation and differentiation
Giuliani N, et al
Blood 2005;106 2472-2483
- The current status of thalidomide in the management of multiple myeloma.
Glasmacher A, von Lilienfeld-Toal M.
Acta Haematol. 2005;114 Suppl 1:3-7
- Risk factors and kinetics of thrombocytopenia associated with bortezomib
for relapsed, refractory multiple myeloma
Lonial S, et al
Blood published 11 August 2005, 10.1182/blood-2005-03-1173
- Combination therapy with lenalidomide plus dexamethasone (REV/DEX) for newly diagnosed myeloma
Rajkumar SV, et al
Blood published 23 August 2005, 10.1182/blood-2005-07-2817
- The combination of the Farnesyl transferase inhibitor (Lonafarnib) and the proteasome inhibitor (Bortezomib) induces synergistic apoptosis in human myeloma cells that is associated with down-regulation of p-AKT
David E, et al
Blood published 23 August 2005, 10.1182/blood-2005-06-2584
- Novel therapy in multiple myeloma (especially for older patients)
Aviles A, et al
Invest New Drugs. 2005 Oct;23(5):411-5.
- CLINICAL TRIALS
If you would like more information about any clinical trial, you can call the IMF Hotline at 800-452-CURE. The Myeloma Matrix has a current list of all myeloma trials from pre-clinical to recently FDA approved. If you would like to browse trials currently open for enrollment, visit the Clinical Trials page of the IMF web site. Among the links, you will find EmergingMed, with whom the IMF has entered into a partnership to assist you in matching trials to your particular patient profile (i.e., stage of disease, previous treatment, how well you are able to carry out the activities of daily living, etc.) and by doing so, increase your chances of being eligible. You can also learn more about clinical trials by reviewing materials from the National Cancer Institute.
UPCOMING SEMINARS AND CLINICAL
Patient & Family Seminar - September 24, 2005|
Patient & Family Seminar - October 7, 2005|
Patient & Family Seminar - October 10, 2005|
Patient and Family Seminar - October 22, 2005|
Patient and Family Seminar - October 28, 2005|
Symposium - November 5, 2005|
with the Arizona Myeloma Network
UPCOMING EVENTS AND EXCITING
The IMF's comprehensive "How-to-FUNdraise"
guide is what you need if you're thinking about fundraising in your
community, but don't know where to start. The guide will give you the "A
to Z" of fundraising ideas, and other helpful
See complete list of 2005 UPCOMING
SHOP FOR THE IMF
Shop at leading internet retailers (e-tailers) like Amazon.com, and they will donate a portion of your
purchase to the IMF. To do this, you access their site via special URLs we
have set up. For Amazon, it's http://amazon.myeloma.org instead of amazon.com. It will
take you to the same place, but any purchase you make during that visit
will be credited to the IMF. Visit our Shop for
the IMF page at http://shop.myeloma.org for express links to other
popular etailers who will donate a portion of your purchase to the
|Our own Rosanne Kalick, who co-leads the Westchester, NY support group, has written a book titled "Cancer Etiquette: What to do, what to say, when someone you love has cancer." You can order now at a discount.
"The more I investigated, the more convinced I became that most people do not know what to say or what to do when someone they know or love has cancer. This book will help them find words that will not offend or hurt, but will help to comfort. This book will enable them to perform simple acts of loving-kindness that are blessings to the patient."
New! Multiple Colors for Multiple Myeloma Keychains and Earrings
The gift-giving holidays will be upon us sooner than we think. And there are always birthdays, anniversaries, and "just because you're you" occasions. Here are two new items to help support the International Myeloma Foundation: colorful keychains and chandelier earrings of Swarovski crystals.
Imagine Moving Forward is the theme of the IMF's popular myeloma bracelet. At medical
conferences and patient & family seminars we see people wearing them
in honor, celebration, or in memory of a loved one. They're only $1 each
in sets of 10, so order them for everyone you know who has been touched by
myeloma. Order them on the web. If you have questions about the
bracelets or would like more information, contact Suzanne Battaglia at
(800) 452-2873, ext. 227, or SBattaglia@myeloma.org.
Multiple Myeloma Awareness
The response has been great for the new garnet bracelet
IMFer Kristi Difford has added to her line of beautiful custom bracelets
to honor those who have joined the struggle against multiple myeloma.
See more exciting ways to help the IMF continue its
important work in education, support and
The HealthWell Foundation has recently opened the
Multiple Myeloma fund to help even more patients gain access to the best
health care available. You can contact them at (800) 675-8416 or
Access Network Foundation (PANF) provides copay assistance for
myeloma. Thalomid is the MRDD product covered for this condition. The
PANF formerly just covered qualified myeloma patients_ erythropoietin
alpha expenses. Patients or healthcare providers may initiate the
application process. Applications must be completed by both physician
and patient, and income verification is required. Their phone number is
|Help Us Help Others...|
As a non-profit organization, the
IMF is completely dependent on the support of our members. Tax-deductible
donations in honor of a friend or family member make great gifts and are a
wonderful way to celebrate a special occasion. You can donate
online or by calling the IMF at (800) 452-CURE. We sincerely thank you
for your support.