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Sydney 2005: In MM 14q32 Transloc. are Present in Memory B Cells but RAS Mutations are Restricted...
By Thomas Rasmussen, MD
Dr. Rasmussen presented on MM14q32 translocations. Researchers have not yet identified which cells are involved in the genetic events necessary for the development of MM. Rasmussen and colleagues looked at memory B cells to find out whether those cells contain the same genetic memory that is seen in MM plasma cells. Although B cells have some of the characteristics on MM plasma cells, B cells do not have the key characteristics of plasma cells that develop into malignant MM plasma clone cells.

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