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Sydney 2005: In MM 14q32 Transloc. are Present in Memory B Cells but RAS Mutations are Restricted...
By Thomas Rasmussen, MD
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04.11.05 |
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Dr. Rasmussen presented on MM14q32 translocations. Researchers have not yet identified which cells are involved in the genetic events necessary for the development of MM. Rasmussen and colleagues looked at memory B cells to find out whether those cells contain the same genetic memory that is seen in MM plasma cells. Although B cells have some of the characteristics on MM plasma cells, B cells do not have the key characteristics of plasma cells that develop into malignant MM plasma clone cells.
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