- SwRI Receives $1.6 Million DOD Contract to Develop Bone-Targeting Nanocapsules
The program is intended to determine, in pre-clinical studies, the potential of skeletally targeted proteasome inhibitors as an effective and selective treatment for myeloma. Proteasome inhibitors have been under study as a treatment for myeloma and other cancers. They limit the function of the proteasome, part of the cell machinery responsible for cleaning up proteins involved in cellular function once they have completed their task. (from BusinessWire)
- New Frontiers for Cancer Pain Medication
Opioids are still the drug of choice for managing severe cancer pain, but there are new treatments that have recently been approved by the FDA that are stronger and have fewer side effects. One of them, Prialt® (ziconitide), is synthetically derived from the venom of a small, poisonous marine snail, the Conus magus. (from CUREXtra)
- Mayo inventers granted patent for method by which myeloma is detected based on determination of concentrations of bioactive IL-1.beta.
The invention is based on the discovery that bioactive IL-1.beta., while undetectable in normal plasma cells, is abnormally expressed in the plasma cells of virtually all myeloma patients and approximately 25% of patients with related plasma proliferative disorders, such as MGUS or SMM. The invention includes diagnostic methods for the detection of MM and the identification of high-risk MGUS and SMM patients likely to progress to active MM. (PDF of Patent)
- PacMab in Australia raises $700,000 for new cancer therapy -- humanised monoclonal antibodies -- that binds to an antigen expressed exclusively by multiple myeloma cells.
The funds will assist development of their lead drug which is in late stages of preclinical testing. The company is already preparing for Phase I and Phase IIa clinical trials. (from PacMab)
- Man raises awareness of myeloma
A very nice article about IMFer Peter Tischler, founder of the North Texas Myeloma Support Group. (from the Star Telegram)
- Coping with a loved one's cancer
It is easy to imagine ourselves as veritable Florence Nightingales, dispensing soothing words with the medication and comfort with the tea and toast. But the reality is that, while caring for a loved one with a serious illness can be a hugely satisfying act of love, it can also be an exhausting and frightening experience. (from Scotsman.com)
WHAT'S NEW IN RESEARCH
- VELCADE® trials
- THALOMID® trials
- TRISENOX™ trials
- REVLIMID™ trials
- DOXIL trials
- EVEREST (Evaluation of VELCADE Employed as Retreatment for Efficacy, Safety, and Tolerability)
A multicenter phase IV clinical trial of VELCADE in multiple myeloma (MM) patients who have previously responded to VELCADE and relapsed following a treatment-free remission. Efficacy of retreatment with VELCADE will be assessed in terms of best confirmed M-protein response.
For more information, the Myeloma Matrix has a current list of all myeloma trials from pre-clinical to recently FDA approved. If you would like to browse trials currently open for enrollment, visit the Clinical Trials page of the IMF web site. Among the links, you will find EmergingMed, with whom the IMF has entered into a partnership to assist you in matching trials to your particular patient profile (i.e., stage of disease, previous treatment, how well you are able to carry out the activities of daily living, etc.) and by doing so, increase your chances of being eligible. You can also learn more about clinical trials by reviewing materials from the National Cancer Institute.
UPCOMING SEMINARS AND CLINICAL CONFERENCES
- The IMF is celebrating its 15th Anniversary Gala Hollywood style with Lights, Camera, Action, Cure! on November 12th at the Beverly Hilton Hotel, home of the Golden Globes. If you are interested in being involved with this year’s planning committee, we would love to hear from you. Contact Candace McDonald, Associate Director of Development at email@example.com or call at 800-452-2873 x 222.
- 6th Annual JC Golf Tournament - May 21, 2005
Saint Cloud, Minnesota
- Leona Cravotta Memorial Golf Tournament - May 22, 2005
- Key Bank Vermont City Marathon- May 29, 2005
- See complete list of 2005 UPCOMING EVENTS.
ITEMS OF INTEREST
- Back By Popular Demand!
Many of you expressed an interest in participating in the Quilts of Courage, but the project was so successful we sold out quickly on the available squares. We’ve decided to do one more, and if you’re interested in participating, please contact IMFer Harriet Bertsche via email at firstname.lastname@example.org or (914) 478-4689 remember, they sell quickly! It’s a wonderful way to honor mom/dad/sister/brother/friend.
- New! Donate to the IMF with your American Express Card
• Donate dollars
• Donate Membership Rewards® points
• Set up recurring donations
For more information, contact Candace McDonald at email@example.com
- Volume II of Cooking with the IMF
The collection of recipes for Volume II of our very popular healthy food cookbook is being led by Marilyn Alexander, a myeloma survivor from Philadelphia. Please help us with this important project by submitting your favorite recipes.
SHOP FOR THE IMF
- It's spring, and if you are looking for something special for that special someone, look no further. Many of the internet's most popular merchants--places you would patronize anyway--will donate a portion of your purchases to the IMF if you enter their sites using the links on our Shop For The IMF page or the special links below.
- New Items! Multiple Myeloma Awareness Jewelry
In time for Mother's Day, IMFer Kristi Difford has added two necklaces and two sets of matching earrings to her line of beautiful custom jewelry to honor those who have joined the struggle against multiple myeloma. Kristi will only take Mother's Day orders until April 12, so don't delay!
- Save on Mother's Day Jewelry
IMFers Esther and Herman Adler sell jewelry at wholesale prices and want to remind you that if you tell them you are an IMFer when you make a purchase, a portion of the proceeds will be donated to the IMF.
- Wine Vests
You don't have to look "Sideways" to love wine and to appreciate IMFer Caethe Goetz' adorable vests for wine bottles. A portion of each sale will be donated to the IMF.
- Michael Tuohy's CD of his Song "I'm Not Leavin'"
Michael Tuohy wrote this uplifting song for his two young children to reassure them that he would win his battle with cancer. There are two versions on the CD, on one there is a gentle acoustic version and on the other Michael rocks. 100% of the proceeds of this CD are being donated to the IMF.
- The Catlett Card Series
The Catlett Cards are designed by Irma Catlett in memory of her husband Lou. All proceeds go to support the programs of the IMF.
Help Us Help Others...
As a non-profit organization, the IMF is completely dependent on the support of our members. Tax-deductible donations in honor of a friend or family member make great gifts and are a wonderful way to celebrate a special occasion. You can donate online or by calling the IMF at (800) 452-CURE. We sincerely thank you for your support.