- New! Understanding Thalidomide Therapy on the Web
Read it on the web or download and print the PDF document. Available in English, Spanish, French, German, and Italian.
- FDA approves Genta's Ganite for cancer-related hypercalcemia
Cancer-related hypercalcemia, common in myeloma, is a life-threatening elevation of blood calcium that can occur in up to 50% of patients with advanced cancer. (from Yahoo News)
- Genetic variations may predict treatment responses for myeloma
Researchers from The Cancer Center at the University of Minnesota have demonstrated that variations in genes may determine the outcome and toxicity of treatments for myeloma cancer patients. The findings support thinking that physicians may optimize care by adjusting treatment according to a patient's specific genetic condition. (from Business Wire) See related story "Genetic analysis is yielding more information on the complicated formation and progress of multiple myeloma" below.
- Families Need to Prepare for the Adversities of Aging
"Most people walking the street right now think, I have Medicare; I'm covered. Wrong," (from the Los Angeles Daily News)
- Ribbon of Hope Making A World of Difference Anniversary Gala
October 4, 2003
Paul Allen's Experience Music Project Museum in Seattle, WA
The evening promises to be the best ever! The EMP is Seattle's most unique architectural wonder, housing a new interactive museum that combines performance space, technology and revolutionary architecture in a facility created to celebrate the heritage and anticipate the future of American popular music.
- GPC Biotech Presents Promising, New Data on 1D09C3 Anticancer Monoclonal Antibody in Combination with Rituxan
We covered GPC's update on 1D09C3 in the August 24 Myeloma Minute. This press release, picked up by Yahoo Finance, reports that the cure rate of the combination was consistently higher than with either agent alone.
What's New in Myeloma Research:
- Genetic analysis is yielding more information on the complicated formation and progress of multiple myeloma.
The mechanisms of MM development remain enigmatic. Here researchers discuss recent progress made in addressing those mechanisms through the molecular dissection of the transcriptome of normal PCs and MM.
- A new conditioning regimen involving total marrow irradiation, busulfan and cyclophosphamide followed by autologous PBSCT in patients with advanced multiple myeloma.
Einsele H, Bamberg M, Budach W, Schmidberger H, Hess CF, Wormann B, Meisner C, Straka C, Hebart H, Trumper L, Kroger N, Zander AR, Hegewisch-Becker S, Hossfeld DK, Schmidt H, Muller P, Schlimok G, Hertenstein B, Peest D, Metzner B, Frickhofen N, Kanz L, Bensinger WI.
Administration of this intensified conditioning regimen was associated with tolerable toxicity, a high response rate and long EFS and OS.
- Rheumatoid Synovium; X-box binding protein-1 is involved in plasma cell differentiation
And XBP-1 plays an important role in the regulation of interleukin-6 production, a cytokine essential for plasma cell survival.
What's New in Clinical Trials:
If you would like to browse trials currently open for enrollment, visit the Clinical Trials page of the IMF web site. Among the links, you will find CenterWatch and EmergingMed. The IMF has entered into partnerships with them to assist you in matching trials to your particular patient profile (i.e., stage of disease, previous treatment, how well you are able to carry out the activities of daily living, etc.) and by doing so, increase your chances of being eligible. You can also learn more about clinical trials by reviewing materials from the National Cancer Institute.
- Medicare talks moving slowly in Congress
The slow pace of Medicare negotiations is stirring talk that lawmakers might not pass a comprehensive drug benefit bill this year, pushing the issue into the politically charged presidential election year. (from Boston Globe)
- Governors unified on prescription drugs
The nation's governors are setting aside partisan rifts over other Medicaid reforms to bolster their united stand behind a congressional plan to provide prescription drug benefits to low-income seniors. (from the Associated Press by way of the Fort Wayne News Sentinel)
Upcoming Seminars and Conferences:
- Heidelberg Patient & Family Seminar
September 26-28, 2003
- Philadelphia Patient & Family Interactive Seminar
October 17-18 2003
- Tokyo Patient & Family Seminar
November 2, 2003
- Dallas Patient & Family Interactive Seminar
Baylor University Medical Center
November 7-8, 2003
- IVth International Conference on Cancer-Induced Bone Diseases
San Antonio, Texas
December 7-9, 2003
Put on by the Paget Foundation, conference will cover the spectrum of bone metastases caused by breast cancer, prostate cancer, and osteolyic lesions due to myeloma. IMF Board Member Gregory R. Mundy, MD is Conference Chair.
FUNdraising Made Easy
You know you want to do something, but deciding on what to do can be confusing. The IMF can help. This year, our members really rallied 'round the cause, picked up the gauntlet, and raised a lot of money for myeloma research and programs.
We are already getting calls from new members who want to join in the effort and hold an event in 2004. Suzanne Battaglia is waiting for your call. She is here to help you plan and execute your event, so please write, call or email (SBattaglia@myeloma.org) so that you can get on our Calendar of Events!
See what you can do in your community to help further the goal of finding the cure!
Items of Interest:
- The National Cancer Institute (NCI) Office of Education and Special Initiatives is looking for patients, family caregivers, and physicians who are interested in participating in telephone focus groups and in-depth interviews. Payment will be provided to all participants.
- BANK ON A CURE®
BANK ON A CURE is an innovative and powerful concept designed to establish a method to find new treatments for multiple myeloma and other related diseases as well as the possibility of new cures, while customizing care for current patients.
- Myeloma Matrix
The Myeloma Matrix provides updated information about drugs beginning with pre-clinical developments and tracks drugs as they proceed through Phases I III of clinical trials, drugs that have been FDA approved, and information on trials that are being conducted by NCI- sponsored cooperative groups as well as other myeloma study groups. The online version is updated regularly. If you would like to have a printed copy, call the toll-free hotline (800) 452-2873.
- International Prognostic Index
The International Myeloma Foundation is proud to sponsor the International Prognostic Index (IPI) Classification for Multiple Myeloma. Nearly twenty myeloma institutions from around the world are collaborating to create an updated staging system for multiple myeloma.
- NexCura Cancer Profiler
The Cancer Profiler is a free service (no hidden fees or charges). Its tools provide you with information specific to your cancer diagnosis to help you make more informed treatment decisions along with your physician.
- Expert Opinions on Multiple Myeloma
A multimedia, CME-accredited program for physicians with the chance to see world-renowned myeloma specialists sharing their knowledge, discussing treatment choices, and comparing their perspectives on controversial issues in multiple myeloma and related diseases.
- Myeloma At The Movies
It has been our goal to bring our Patient & Family Seminars to people around the country who might not be able to attend an actual meeting, so we have set up a video lending library.
- HealthTalk's Multiple Myeloma Education Network
Put this site in your favorites folder.
Shop for the Cure!
Many of the internet's most popular merchants will donate a portion of your purchases to the IMF if you enter their sites using the links on our Shop For The Cure page. You can also use the special shortcut URLs listed below:
So, Shop For The Cure by using these links to the same get great service and low prices you're used to while helping support the IMF!
Help Us Help Others...
As a non-profit organization, the IMF is completely dependent on the support of our members. Please consider showing your support by making a tax-deductible donation today. Donations in honor of a friend or family member make great gifts and are a wonderful way to celebrate a special occasion. You can donate online or by calling the IMF at (800) 452-CURE. We sincerely thank you for your support.
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